Typically if you have both extremes of the political spectrum mad at you, you should be doing good. Senator Blanche Lincoln (D-AR) is not feeling the love of a majority of Democrats in Arkansas.
Taking only 43% of the vote in the Arkansas Democratic primary doesn’t show she is properly endeared by the party. According to The New York Times, this is due to her flip flopping on issues.
Goodness. Politicians are known for that, but in this anti-incumbent atmosphere, a little more backbone and exhibition of solid position may help.
Those who dare call themselves centrists may want to take heed. Centrism has to stand for something. People may not agree with you (or so you might think), but they will respect you for not engendering uncertainty in their voting decisions.